Lab Equipment

Superconducting Magnet System

7T horizontal superconducting magnet, Pharmascan 70/16 AS, Bruker Corporation

• Magnetic screening: active
• Field-strength: 7.0 T (300.3 MHz for 1H)
• Distance front flange to ISO-center: 506 mm
• Liquid Helium hold-time: > 100 days
• Liquid Nitrogen hold-time: > 14 days

Actively shielded gradient system BGA-9A HP with a full set of 2nd order shims

• Inner diameter 90 mm
• Gradient strength: 760 mT/m at 200 A
• Max. linear slew rate: 6840 T/m/s
• Duty cycle, max simultaneous DC current: 3x46 A

Spectrometer Electronics

Avance III Electronics

• Automatic hardware recognition system for basic system components like amplifiers and RF coils.
• RF Preamplifiers for Protons
  • 1H low noise preamplifier including T/R switch
  • Active detuning device
• RF quadrature combiner
• RF tune/match adapter
• RF interface adapter for operation of home-built or 3rd party RF coils

Gradient electronics

• High-power gradient amplifier: 300 V / 200 A
• Gradient chiller system
• Shim interface
• Shim amplifier (6 channels, max current 5A)

RF electronics

• 1H RF amplifer for proton MRI/MRS excitation, 300 W
• Broadband receiver with integrated AD converter
• Digital multi-receiver channel system

RF Resonators

Mouse head quadrature volume resonator

• No tune/no match, optimized for mouse brain loadings
• Transmit/receive capabilities
• Outer/inner diameter = 55mm/23mm
• Bruker Corporation, Model No: MT0206.

Rat head/Mouse body quadrature volume resonator

• Tunable and matchable coil for rat brain or mouse whole-body loadings
• Transmit/receive capabilities
• Outer/inner diameter = 75mm/40mm
• Bruker Corporation, Model No: MT0205.

Rat body quadrature volume resonator

• No tune/no match, optimized for rat whole-body loadings
• Transmit/receive capabilities
• Outer/inner diameter = 89mm/69mm
• Bruker Corporation, Model No: MT0013.

Rat Brain Array Surface Coil

• 4 element rat brain surface coil
• 1H, 2x2 coil element topology
• Receive-only capabilities
• Bruker Corporation, Model No: MT0044-01.

Mouse Brain Array Surface Coil

• 4 element mouse brain surface coil
• 1H, 2x2 coil element topology
• Receive-only capabilities
• Bruker Corporation, Model No: MT0045-01.

Planar Surface Coils, 10mm, 20mm and 30mm

• No tune/no match flexible end
• 1H, to be used in combination with a local preamplifier
• Receive-only capabilities
• Bruker Corporation, Model No: MT0105-10, -20, -30

Transmit-only Volume Coil for Mice and Rats - 72 mm

• Transmit-only coil capabilities, to be used in combination with receive-only coils
• Active coil decoupling in cross-coil setups
• 1H, circularly polarized
• Outer/inner diameter = 89mm/72mm
• For rodents up to 450 g body weight
• Bruker Corporation, Model No: MT0380.

Workstation and Peripherals

Bruker desktop MR-workstation

• 8GB RAM, 1000 GB hard disk
• running CentOS Linux operating system

Additional workstation for external data processing (located in the MIC analysis room on the 6th floor of BBB)

• 4GB RAM, 500GB hard disk
• running CentOS Linux operating system

Color monitor 24"
Printer

Software

• ParaVision 6.0.1 Basic Package
• ParaVision Extension Package
  • Ultrafast Imaging Package (EPI sequences)
  • Angiography Package (2D inflow, Phase Contrast)
  • Ultra short TE (UTE) Package
  • Image Algebra and Fit Package
  • 3D Image Processing Package
• Paravision Spectroscopy Package
• Paravision Data Manager
• Paravision Diffusion Tensor Imaging Package
• Intragate (for retrospectively triggered cardiac imaging)

Animal Monitoring and Handling Equipment

Animal Beds

• Animal bed for mouse brain/head/body applications
  • Bed tip for mouse brain applications (to be used with the mouse brain phased-array coil)
  • Bed tip for mouse head applications (to be used with the mouse head quadrature volume coil)
  • Bed tip for mouse whole-body applications (to be used with the mouse body quadrature volume coil)
• Animal bed for rat brain/head applications
  • Bed tip for rat brain applications (to be used with the rat brain phased-array coil)
  • Bed tip for rat head applications (to be used with the rat head/mouse body quadrature volume coil)
• Animal bed for rat body applications
  • Bed tip for rat whole-body applications (to be used with the rat body quadrature volume coil)

BioTrig Life Monitoring System: System for display and analysis of physiological signals during animal examinations. Developed for the synchronization of MR acquisitions by using ECG or respiration triggering signals.

• MRI compatible temperature probe from SA Instruments
• Pressure sensor for respiration monitoring and triggering from SA Instruments
• Pulse oximeter module with sensors for mouse and rat tail/ankles from SA Instruments
• ECG electrodes for cardiac triggering from SA Instruments
• Animal heating blankets with recirculating warm water.

• Manual describing the operation of the Animal Monitoring and Handling Equipment pdf

Other Equipment

• Syringe Pump (Harvard Programable PHD 2000)
• Manual describing the operation of the syringe pump pdf